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Intracellular Signal Transduction: The JAK-STAT Pathway by Andrew F. Wilks
Intracellular Signal Transduction: The JAK-STAT Pathway by Andrew F. Wilks
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Intracellular Signal Transduction: The JAK-STAT Pathway

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Description

This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilising the STAT (Signal Transducers and Activators of Transcription) transcription factors. The basic components of the JAK/STAT pathway are covered in detail, and the centre piece of the book is a guided tour of the pathway itself. An interesting addition to the book is the chapter on the use of Drosophila melanogaster as a genetic system to probe the pathway at the whole organism level. The book is targeted to researchers who have an interest in intracellular signalling.
Release date NZ
November 13th, 2013
Audience
  • Professional & Vocational
Edition
Softcover reprint of the original 1st ed. 1996
Illustrations
30 Illustrations, black and white; VII, 209 p. 30 illus.
Pages
209
Dimensions
178x254x12
ISBN-13
9783662220528
Product ID
21808641

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