I Domains in Integrins

Name: I Domains in Integrins
SKU: 5582923
Price: 446.00 NZD
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Hardback

Series:

Molecular Biology Intelligence Unit

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Description

In vertebrates, the integrin family includes 24 members. As the a-chains were sequenced, some were observed to have an inserted domain similar to the A domain in several matrix and complement proteins. This inserted ligand binding domain is interactive and was called the I domain in integrins. More recently structural data have shown that an integrin b-chain also contains an I domain. Nine of the currently known 18 a-chains contain an I domain. This book systematically goes through the contemporary knowledge about these integrins, including the newest additions to the integrin family, the collagen-binding a10b1 and a11b1 integrins. The book discusses ligand binding, signalling properties, knock-out phenotypes and possible involvement in disease. It comprehensively reviews contemporary knowledge about I domains in integrins and should serve as a useful reference book for scientists in this field.

Release date NZ

July 31st, 2003

Audiences

Postgraduate, Research & Scholarly
Professional & Vocational
Undergraduate

Contributor

Edited by Donald Gullberg

Illustrations

X, 186 p.

Pages

186

Series

Molecular Biology Intelligence Unit

Dimensions

152x229x19

ISBN-13

9780306478369

Product ID

5582923

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