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The mystery of Revelation is unfolded by the Prophet, the Lord Jesus Christ. Revelation is based on the prophetic themes of the Old Testament and the development of those themes in the Olivet Discourse. This commentary integrates the book of Zechariah, most of the book of Daniel, and several chapters from other visionary prophets with the message of Revelation. The world is in the throes of the labor pains of the end times. Bible prophecy alludes to the nations that will be of worldwide concern during these times: England, the United States, Russia, Israel, and several Middle East nations. Persecution of Christians and Jews, terrorism, and Satanism are prophesied. The Scriptures tell of a Great Middle East War that will occur at the end of the Great Tribulation where weapons of mass destruction may be used. The relevancy of prophecy to the current world situation is discussed throughout this commentary. During his medical career, the author has studied internal medicine, geriatrics, and infectious diseases and been credentialed in these fields. He has published in scientific journals in the discipline of infectious diseases. His medical fellowships include the American College of Physicians, the American College of Physician Executives, and the American College of Healthcare Executives. He has held several administrative positions at an executive level. He has published in Christian periodicals on the subject of "Medicine and the Scriptures" and authored a prior book, The Twelve Generations of the Creation with Biblical Timelines from Adam to Christ (Longwood, FL: Xulon Press, 2007). He is a past Dean of a Christian medical school. He has served on several boards of churches and Christian organizations. He has taught group Bible studies for over four decades. In order to better understand the Bible, he has studied Hebrew and Greek.