Non-Fiction Books:

The Cardiovascular Glycocalyx in Health and Disease

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Description

The Cardiovascular Glycocalyx in Health and Disease, Volume 91 gives updates on the glycocalyx function through the cardiovascular system and its integration in whole system physiology. Chapters address Endothelial surface layers in the kidney, Pharmacological targeting of the glycocalyx -- current status and prospects, The endothelial glycocalyx and the subtleties of female microcirculation, and much more targeted content.

Author Biography:

Dr. Fancher is an Assistant Professor at the University of Delaware in the Department of Kinesiology and Applied Physiology, College of Health Sciences. Dr. Fancher’s immediate interests are in understanding how cardiovascular risk factors, such as obesity, impair vascular endothelial ion channel function which ultimately results in dysregulation of vascular function. His recent studies have detailed a link between damage to the endothelial glycocalyx and impaired K+ channel function in obesity; a mechanism he proposes contributes to obesity-induced vascular dysfunction. Ongoing studies in the lab are focused on determining the mechanistic link between elevated macronutrients associated with a poor Western diet and obesity, disruption of the glycocalyx, and K+ channel function. Dr. Andreia Z. Chignalia is an Assistant Professor at the University of Arizona, Department of Anesthesiology, College of Medicine-Tucson. The research in the Chignalia lab focuses on studying the redox mechanisms underlying cardiovascular diseases and associated pulmonary complications. Special emphasis is given to explore the differential redox-sensitive pathways activated by individual glycocalyx components during disease progression. Her research program utilizes a broad range of techniques that span from in vitro, in situ, and in vivo animal models of disease with a translational approach to advance the understanding of human disease with the goal to identify new targets for drug development.
Release date NZ
April 11th, 2023
Audience
  • Professional & Vocational
Contributors
  • Volume editor Andreia Z. Chignalia
  • Volume editor Ibra S. Fancher
Pages
166
ISBN-13
9780443191596
Product ID
36204022

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