Natural drugs have the potential to improve human life and the economy through their applications in medical, biotechnology, agriculture and food science. A majority of the world still relies heavily on antimicrobial herbs for their primary health care. In present global scenario, natural antimicrobial herbs are gaining prominence, because they are economical, easily available and relatively free from side effects. The literature on antimicrobial herbs is growing rapidly, researchers are persistently attempting to decode the many secrets surrounding antimicrobial herbs. antimicrobial herbs is connected to the human aspiration and belief that drugs developed from these plants or by using natural models of these compounds could help in the search for future cures to serious diseases. We hope that the students of degree, post graduate classes in pharmacy, botany & biomedicine, as well as, personnel enganged in pharmaceutical, biotechnology, agriculture, food science and plant based industries shall be benefited by our efforts & should acquire balanced knowledge of antimicrobial herbs.