With time progression, tannases has shown immense importance due to its commercial viability and its complexity as a catalytic molecule. It has already proven to have potential applications in food, feed and pharmaceutical industries. Tannins, the main chemical group of natural anti microbials occurring in plants is hydrolyzed by tannases. The production economics depends on the tannic acid (tannin) concentration thus obtained from biomass of agro residues. In this book, the work is divided into eight major chapters which outlines about the concept of tannase in terms of scientific and technological exploration. Herein, the optimal conditions for tannase production through microbial route have been discussed. In next few chapters, purification, description of the enzyme properties, and the commercial applications to the "perspectives" including expression studies, regulation, and its potential uses has been studied.