A Little Goes A Long Way. Plucky, pint-sized hero Stuart Little (voiced by Michael J. Fox) returns in Stuart Little 2 delighting audiences with his big heart and even more action-packed adventures. Thsi time, Stuart embarks on a journey through the city with a reluctant Snowbell to rescue his new feathered friend Margalo (Melanie Griffith) from the clutches of the manecing Falcon (James Woods). It's a tall order for a small mouse with a big heart, but as Stuart says: "when you're a friend of Stuart Little, you're a friend for life".