In real estate and facility management cost reduction and sustainability are significant issues. An enormous potential lies in the efficient usage of available space. Another challenge is to use space as a form of contribution to the object of an enterprise in the most efficient way. In this book three space-based methods are described to enable an efficient space management in order to improve the organisational performance, sustainability and buildings environmental auditing. Based on the method's characteristics an enhanced evaluation process was developed suggesting the combined application of all described evaluation methods in order to gain broader knowledge and best results. Methods such as for the analysing and visualisation of spatial structures and its effect on human behaviour patterns (space syntax), for an automated space occupancy (recotech), for an automated allocation of space requirements to available space over time (more space) and for the evaluation of buildings after they have been built and occupied for some time (POE) are presented. Finally a case study will be introduced in order to show evidence that the space syntax theory also works in practice.