Road accidents are the sixth leading cause of death in Central Asia., with a road traffic death rate of 10 to 25 per 100,000. A framework is needed for Central Asia Regional Economic Cooperation (CAREC) member countries to effectively implement CAREC's commitment to road safety. CAREC's strategy envisions making its road corridors safe, efficient, and attractive to motorists. The target is to halve the number of CAREC road corridor fatalities by 2030-translating to 23,000 lives saved and 250,000 serious injuries prevented annually. The strategy builds upon existing strengths within the region, addresses gaps, utilizes good practice, and mitigates risks. This publication embodies the CAREC countries' commitment to make road safety a priority.