This title presents advances in the integration and the optimization of product design and manufacturing systems. The book is divided into three chapters corresponding to the following three main topics: optimization of product design process (mechanical design process, mass customization, modelling the product representation, computer support for engineering design, support systems for tolerancing, simulation and optimization tools for structures and for mechanisms and robots); optimization of manufacturing systems (multi-criteria optimization and fuzzy volumes, tooth path generation, machine-tools behaviour, surface integrity and precision, process simulation); methodological aspects of integrated design and manufacturing (solid modelling, collaborative tools and knowledge formalization, integrating product and process design and innovation, robust and reliable design, and multi-agent approach in VR environment).