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Progress in the Chemistry of Organic Natural Products 115

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Description

This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.
Release date NZ
April 3rd, 2022
Audience
  • Professional & Vocational
Contributors
  • Edited by A.Douglas Kinghorn
  • Edited by Heinz Falk
  • Edited by Ji-Kai Liu
  • Edited by Simon Gibbons
  • Edited by Verena M. Dirsch
  • Edited by Yoshinori Asakawa
Edition
1st ed. 2021
Illustrations
42 Illustrations, color; 102 Illustrations, black and white; VII, 203 p. 144 illus., 42 illus. in color.
Pages
203
ISBN-13
9783030648558
Product ID
35760266

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