Physics at the Biomolecular Interface

Fundamentals for Molecular Targeted Therapy

By:

Ariel Fernandez

Format:

Paperback / softback

Series:

Soft and Biological Matter

Show Hide Adult Content

$293.00

Available from supplier

Usually ships in 3-4 weeks

0 in Trolley

Price Match

Wrap this item as a gift ($5.90) - add a free gift card on the next page

Free Delivery with Primate

Join Now

Free 14 day free trial, cancel anytime.

Buy Now, Pay Later with:

4 payments of $73.25 with Afterpay Learn more

6 weekly interest-free payments of $48.83 with Laybuy Learn more

Availability

Delivering to:

Estimated arrival:

Around 28 Jun - 10 Jul using International Courier

Description

This book focuses primarily on the role of interfacial forces in understanding biological phenomena at the molecular scale. By providing a suitable statistical mechanical apparatus to handle the biomolecular interface, the book becomes uniquely positioned to address core problems in molecular biophysics. It highlights the importance of interfacial tension in delineating a solution to the protein folding problem, in unravelling the physico-chemical basis of enzyme catalysis and protein associations, and in rationally designing molecular targeted therapies. Thus grounded in fundamental science, the book develops a powerful technological platform for drug discovery, while it is set to inspire scientists at any level in their careers determined to address the major challenges in molecular biophysics. The acknowledgment of how exquisitely the structure and dynamics of proteins and their aqueous environment are related attests to the overdue recognition that biomolecular phenomena cannot be effectively understood without dealing with interfacial behaviour. There is an urge to grasp how biologically relevant behaviour is shaped by the structuring of biomolecular interfaces and how interfacial tension affects the molecular events that take place in the cell. This book squarely addresses these needs from a physicist perspective. The book may serve as a monograph for practitioners and, alternatively, as an advanced textbook. Fruitful reading requires a background in physical chemistry and some basics in biophysics. The selected problems at the end of the chapters and the progression in conceptual difficulty make it a suitable textbook for a graduate level course or an elective course for seniors majoring in chemistry, physics, biomedical engineering or related disciplines.

Author Biography:

Ariel Fernández (born Ariel Fernández Stigliano) is an Argentine-American physical chemist and mathematician. He obtained his Ph. D. degree in Chemical Physics from Yale University in record time. He held the Karl F. Hasselmann Endowed Chair Professorship in Engineering at Rice University and was a Professor of Bioengineering until his retirement in 2012. To date, he has published over 350 scientific papers in professional journals including Physical Review Letters, PNAS, Nature, Genome Research and Genome Biology. Ariel Fernandez has also published two books: “Transformative Concepts for Drug Design” (2010) and “Biomolecular Interfaces” (2015), both with Springer, and holds two patents (US. 8,466,154 and 9,051,387) on biotechnological innovations. He is currently involved in research and entrepreneurial activities at various consultancy firms.

Release date NZ

June 20th, 2018

Author

Ariel Fernandez

Audience

Professional & Vocational

Edition

Softcover reprint of the original 1st ed. 2016

Illustrations

208 Illustrations, color; 87 Illustrations, black and white; XV, 483 p. 295 illus., 208 illus. in color.

Pages

483

Series

Soft and Biological Matter

Dimensions

156x234x26

ISBN-13

9783319809007

Product ID

28243995

Customer reviews

Nobody has reviewed this product yet. You could be the first!

Write a Review

Marketplace listings

There are no Marketplace listings available for this product currently.
Already own it? Create a free listing and pay just 9% commission when it sells!

Sell Yours Here