Daan J.A. Crommelin is Professor Emeritus, Department of Pharmaceutical Sciences, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherland. He is an elected fellow of the International Pharmaceutical Federation (FIP) and the American Association of Pharmaceutical Scientists (AAPS). Robert D. Sindelar is a Professor and Dean Emeritus, Faculty of Pharmaceutical Sciences, The University of British Columbia (UBC). He is an elected fellow of the Canadian Academy of Health Sciences, and an elected fellow of the International Pharmaceutical Federation (FIP). He previously served as Vice President of Innovation, Research & Academic Affairs at Providence Health Care (PHC), President of the PHC Research Institute and Associate Dean Research in the UBC Faculty of Medicine Bernd Meibohm is Distinguished Professor, Associate Dean for Research and Graduate Programs, and Chair of the Department of Pharmaceutical Sciences at the University of Tennessee Health Science Center College of Pharmacy, Memphis, Tennessee, USA. He is an elected fellow of the American College of Clinical Pharmacology (ACCP) and the American Association of Pharmaceutical Scientists (AAPS).