Marking its 25th anniversary, this fascinating collection examines the pioneering work of the National Institute for Health and Care Excellence (NICE). Setting standards for the delivery of healthcare, issuing guidance on public health, and assessing and making recommendations on health technologies, NICE has attracted widespread international attention, emulation, and comment. The authors in this collection, drawn from a broad range of disciplinary backgrounds, offer analysis of key issues which have informed NICE’s work, from the principles of health economics, to patient engagement, to the legal basis on which NICE operates. Covering many of the most important themes within contemporary debates on health policy and management today, this insightful collection will interest students and researchers, as well as policy makers in the field.