For SCIENCE! Mutants and Mad Scientists (5E) provides a horrific examination of the magic and mechanics of mutation, blending elements of science fiction and fantasy in a magnificently mutated melange. This product is ideal for 5E spellcasters seeking to create their own mutated minions and awful experiments, but it also deals with the hateful backlash against all manner of mutants. With new class options like the chirurgeon wizard and xenocidist ranger and spells like blightcore meltdown, summon horde of flesh, and the ominously titled one of us to genetic purification and mutagenic reversion, this product covers both sides of the mutant question. This book provides a variety of options for paragons of genetic purity seeking to stamp out the insidious influx of mutants in society. At the same time, mutations and body horror experimentation are just one facet of introducing mad scientists into your 5E campaign! They are a classic trope of the horror genre, and this book brings them to life in a terrifyingly evocative way, focusing on all the awful possibilities of non-magical yet murderous medicine, sadistic surgery, and gruesome grafting. There are echoes of magic alongside the purely technological, as we explore how the cruel science of chirurgery and replicate or counter more common magical means of corrupting or altering body and mind alike with procedures like Implant Psychic Trigger, Lobotomize, Stimulate Adrenal Cortex, and Install Kill-Switch. You can incorporate these options across the campaign to infuse sci-fi and steampunk themes into your game, or you can use the unique tomes included in this book to restrict the terrifying secrets within to only those insane enough to seek them out. The dread libram Omnia Mutandis reveals the inmost secrets of twisting the flesh, while Regarding the Clockwork of Capillaries explicates all the subtle mechanics of the living body and the creation of chirurgical constructs like the cyberphrenic tadpole and cranial dissectibot! Grab this amazing 38-page horror supplement for the 5th Edition of the world's most famous roleplaying game today and Make Your Game Legendary!