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Mitochondrial Disorders Caused by Nuclear Genes
Mitochondrial Disorders Caused by Nuclear Genes
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Mitochondrial Disorders Caused by Nuclear Genes

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Description

Mitochondrial cytopathies are mutations in the inherited maternal mitochondrial genome, or the nuclear DNA-mutation. Mitochondrial respiratory chain disorders (RCD) are a group of genetically and clinically heterogeneous diseases, due to the fact that protein components of the respiratory chain are encoded by both mitochondrial and nuclear genomes and are essential in all cells.  In addition, the biogenesis, structure and function of mitochondria, including DNA replication, transcription, and translation, all require nuclear encoded genes.  Since mitochondria are present in every cell, every tissue, mitochondrial disorder usually affects multiple organs.
Release date NZ
October 15th, 2014
Audience
  • Professional & Vocational
Contributor
  • Edited by Lee-Jun C. Wong
Edition
2013 ed.
Illustrations
XII, 372 p.
Pages
372
Dimensions
155x235x20
ISBN-13
9781489992413
Product ID
22893777

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Cytopathology