Chewable tablets with caffeine, d-ribose and CoQ10 for sports performance.

Chewable tablets that provide pure caffeine to help increase energy expenditure and improve sports performance. D-ribose assists in energy recovery in muscles post-exercise, while coenzyme Q10 (CoQ10) contributes to energy production throughout the body.

CAFFEINE
A cup of brewed coffee contains 95–200mg of caffeine. Coffee has long been consumed for the physiological effects of its caffeine content.

Caffeine may stimulate thermogenesis, resulting in the breakdown of fats stored in adipose tissue and, in combination with exercise, may increase the metabolic rate.[1,3–5]

Once metabolised by the liver, caffeine is broken down into three metabolites: paraxanthine (84%), theophylline (4%) and theobromine (12%). Paraxanthine helps break down fat, releasing it into your bloodstream and fuelling your muscles. Theobromine opens up your blood vessels, increasing the flow of oxygen and nutrients to your brain.[6,7]

It is these effects that can attributed to caffeine possibly improving sports performance,[7–9] with absorption into the blood stream occurring 15–30 minutes after oral administration.

Some people experience a “caffeine crash” with a dropoff in energy levels after the caffeine has been used by the body. The actions of D-ribose and CoQ10, and their elimination times in the body, may lessen this crash effect.[10–13]

D-RIBOSE
Ribose is the sugar that begins the metabolic process for the production of adenosine triphosphate (ATP), the major source of energy used by cells of the body for normal function including muscle tissue.

D-ribose may therefore increase the rate of energy recovery in the muscle after exercise by increasing the rate ATP synthesis.[12,13]

COENZYME Q10
CoQ10 plays an indispensable role in the production of ATP, vital for energy in every cell of the body.

KEY FEATURES AND BENEFITS

• Convenient chewable tablets containing caffeine, D-ribose and CoQ10 for effective intake of nutrients that help support energy production.
• Caffeine may improve sports performance.
• Caffeine may stimulate thermogenesis (heat production), resulting in the breakdown of fat tissue.
• In combination with exercise, caffeine may increase metabolic rate.
• Caffeine is absorbed into the blood 15–30 minutes after being taken orally.[1]
• D-ribose may increase the rate of energy recovery in the muscle after exercise.
• CoQ10 helps support energy production.
• Vanilla-flavoured chewable tablets.

NUTRITION INFORMATION
Each chewable tablet contains:

• Caffeine 25mg
• D-ribose 500mg
• Ubidecarenone (coenzyme Q10) 30mg

References
[1] Jung RT, Shetty PS, James WP, et al, Caffeine: its effect on catecholamines and metabolism in lean and obese humans. Clin Sci (Lond) 1981;60(5):527–535.
[2] Caffeine content for coffee, tea, soda and more. Mayo Foundation for Medical Education and Research 2015. Viewed 29 Dec 2015, http://www.mayoclinic.org/…art-20049372
[3] Acheson KJ, Gremaud G, Meirim I, et al. Metabolic effects of caffeine in humans: lipid oxidation or futile cycling? Am J Clin Nutr 2004;79(1):40–46.
[4] Acheson KJ, Zahorska-Markiewicz B, Pittet P, et al. Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals. Am J Clin Nutr 1980;33(5):989–997.
[5] Astrup A, Toubro S, Cannon S, et al. Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers. Am J Clin Nutr 1990;51(5):759–767.
[6] How caffeine works. FlowAthletics 2013. Viewed 4 Jan 2016, http://flowathletics.com/…feine-works/
[7] Goldstein ER, Ziegenfuss T, Kalman D, et al. International society of sports nutrition position stand: caffeine and performance. J Int Soc Sports Nutr 2010;7(1):5. doi: 10.1186/1550–2783–7–5.
[8] Santos R de A, Kiss MAPDM, Silva-Cavalcante MD, et al. Caffeine alters anaerobic distribution and pacing during a 4000-m cycling time trial. Vinciguerra M (ed). PLoS ONE 2013;8(9):e75399.
[9] Jordan JB, Korgaokar A, Farley RS, et al. Caffeine supplementation and reactive agility in elite youth soccer players. Pediatr Exerc Sci 2014;26(2):168–176.
[10] Busto U, Bendayan R, Sellers EM. Clinical pharmacokinetics of non-opiate abused drugs. Clinical Pharmacokinetics 1989;16:1–26.
[11] Tomono Y, Hasegawa J, Seki T, et al. Pharmacokinetic study of deuterium-labelled coenzyme Q10 in man. Int J Clin Pharmacol Ther Toxicol 1986;24(10):536–541.
[12] Hellsten Y, Skadhauge L, Bangsbo J. Effect of ribose supplementation on resynthesis of adenine nucleotides after intense intermittent training in humans. Am J Physiol Regul Integr Comp Physiol 2004;286(1):R182–188.
[13] Gross M, Kormann B, Zollner N. Ribose administration during exercise: effects on substrates and products of energy metabolism in healthy subjects and a patient with myoadenylate deaminase deficiency. Olin Wochenschr 1991;69:151–155.

• Suitable for adults only. Contains ribose and glucose.
• Do not take while on warfarin therapy without medical advice.
• If symptoms persist consult your healthcare practitioner.
• Vitamin supplements should not replace a balanced diet.
• Always read the label. Use only as directed.