Table of Contents

1. History of Pathological Studies.- 2. Statistics, Epidemiology, and Etiology.- 3. Background Data to the Study of Advanced Gastric Cancer.- Gross Appearances.- Polypoid or Fungating Type.- Circumscribed Excavating Type.- Ulcerated Infiltrating Type.- Diffusely Thickened Type.- Histological Features.- Well-Differentiated Adenocarcinoma.- Moderately Differentiated Adenocarcinoma.- Poorly Differentiated Adenocarcinoma.- Relationship Between Gross Appearances and Histological Features.- Changes in Frequency of Macro- and Microscopical Types by Age and Sex of Patients and Year of Surgery.- Site of Development.- Terminal Stage.- 4. Morphology of Early Gastric Cancer and Related Subjects.- Definition of Early Gastric Cancer and its Significance.- Age and Sex of Patients with EGC.- Gross Appearances and Histogical Features of EGC.- Polypoid Protruding Type.- Broad-Based, Elevated Type.- Focal Depressed Type.- Large Eroded Type.- Peptically Ulcerated Type.- Frequency of Macroscopical Type of EGC.- Relationship Between Macroscopical Appearances and Histological Features of EGC.- Changes in Frequency of EGC and its Macroscopical Types over Time.- Macroscopical Diagnosis of EGC.- 5. Histogenesis.- Macroscopical and Histological Relationships Between EGC and AGC.- Polypoid Protruding Type.- Broad-Based Elevated Type.- Focal Depressed Type.- Large Eroded Type.- Peptically Ulcerated Type.- Histogenesis of EGC.- Minute Focal Cancer.- Superficial Cancer Without Perceptible Macroscopical Change.- Double or Multiple Foci of EGC.- 6. Precursors of Early Gastric Cancer.- Gastric Polyp.- Chronic Peptic Ulcer and Ulcer Scar.- Chronic Atrophic Gastritis and Intestinal Metaplasia of Gastric Mucosa.- Pernicious Anemia.- Gastric Remnant.- Menetrier's Disease and Aberrant Pancreas.- Gastric Dysplasia Including Borderline Lesion.- Summary on Precancerous Changes in the Stomach.- 7. Chronologic Development and Prognosis of Early Gastric Cancer.- Development and Growth.- Prognosis.- 8. Histological Diagnosis of Early Gastric Cancer by Biopsy Examination.- Results of Histological Examination of Biopsied Specimens.- Clinical Implications of Biopsy Findings.- 9. Theories on the Histogenesis and Pathogenesis of Gastric Cancer.- Histological Correlation Between MGC and the Surrounding Mucosa from the Viewpoint of Generative Cells.- Morphogenesis of the Depressed Lesion of MGC and EGC.- Histological Conditions in Gastric Mucosa Before Development of Cancer.- Development of Gastric Cancer from the Viewpoint of Animal Experiment and Basic Study.- 10. Subject Index.