Herbal remedy, a kind of treatment of illness using various plant parts, is now gaining importance. Worldwide people now evince increased interest in medicines of plant origin in preference to synthetic drugs, primarily because of a high degree of adverse side effect associated with the latter. Herbal cure to world's most preponderant chronic endocrine disease 'diabetes' is securing global acceptance, and this has emphasized on modern scientific exploration, extraction and evaluation of folk medicines from plants. This compendium covers over 264 plants describing their identifying features, chemical constituents and their mode of uses in the treatment of various stages of diabetes and/or associated ailments. This monograph is primarily meant for students and researchers of pharmacy, pharmacognosy and herbal healers to acquaint themselves with the occurrence and botanical features of some important anti-diabetic plants. This endeavour will certainly facilitate locating and correctly identifying these natural treasure in order that their active anti-diabetic principle could be exploited with unequivocal accuracy and authenticity.