This thoroughly revised second edition covers the major areas of research, theory, and practical application in health communication. This textbook takes an in-depth approach to health communication by analyzing and critically evaluating research conducted across multiple paradigmatic perspectives and focusing on translational application of research findings. Using the story of the Montgomery family, a biracial, multigenerational family, and their health experiences as a case study, chapters explore topics including patient–provider communication, health communication in the media, ethical issues, and public health crises. New chapters cover the potential for communication to address discrimination in healthcare settings, health information seeking, social support and caregiving, and the relationship between health and environmental communication. Chapters offer pedagogical features that will prove useful to students and instructors of health communication, such as summary boxes, theory tables, suggestions for in-class activities, discussion questions, and lists of additional resources. Developed for use in advanced undergraduate and master’s level health communication and public health courses, this text represents the breadth and depth of health communication theory and research as it exists today. Online resources for instructors including additional theory tables, PowerPoint slides, test questions and assignments, sample syllabi, and lists of additional resources are available at https://www.routledge.com/9781032100470.