This Fourth Edition of Handbook of Solvents, Volume 2, contains the most comprehensive information ever published on solvents as well as an extensive analysis of the principles of solvent selection and use. The book begins with a discussion of solvents used in over 30 industries which are the main consumers of solvents. The analysis is conducted based on the available data and contains information on the types (and frequently amounts) of solvents used and potential problems and solutions. Picking up where Handbook of Solvents, Volume 1 leaves off, Handbook of Solvents Volume 2 provides information on the methods of analysis of solvents and materials containing solvents, with 2 sections containing standard and special methods of solvent analysis, followed by a discussion of residual solvents left in the final products. The environmental impact of solvents, such as their fate and movement in the water, soil, and air, fate-based management of solvent-containing wastes, and ecotoxicological effects are discussed as are solvents’ impact on tropospheric air pollution. The next 2 chapters are devoted to the toxicology of solvents and regulations aiming to keep solvent toxicity under control. The analysis of the concentration of solvents in more than 15 industries, specific issues related to the paint industry, and characteristics of the environment in automotive collision repair shops are followed by a thorough discussion of regulations in the USA and Europe. Following chapters show examples of solvent substitution by safer materials, with an emphasis on supercritical solvents, ionic liquids, deep eutectic solvents, and agriculture-based products, such as ethyl lactate. Discussion of solvent recycling, removal, and degradation includes absorptive solvent recovery, comparison of results of recovery and incineration, and application of solar photocatalytic oxidation. The book concludes with an evaluation of methods of natural attenuation of various solvents in soils and modern methods of cleaning contaminated soils.