Gap Junctions in Development and Disease

Name: Gap Junctions in Development and Disease
SKU: 5807072
Price: 450.00 NZD
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Description

Communication between cells via intercellular channels - gap junctions - appears essential to certain developmental processes and appropriate organ function. Gap Junctions in Development and Disease aims to describe the molecular events underlying impaired development and disease. Beginning with a comprehensive review of various mouse and human genes encoding the channel-forming connexins, later chapters describe several connexin mutations associated with human diseases such as hereditary deafness and female infertility. Erroneous signaling mediated by the interaction of mutant connexins with other proteins, thought to be responsible for disfunction of organs such as heart, muscle, brain, skin, lens, placenta, and endocrine tissue in both mice and men, is also addressed.Although the question of why some mutations in gap-junction proteins lead to specific phenotypes remains to be answered, the reviews in this book provide an intriguing insight into the future direction of this research field.

Release date NZ

July 19th, 2005

Audience

Professional & Vocational

Contributor

Edited by Elke Winterhager

Edition

2005 ed.

Illustrations

10 Illustrations, color; 37 Illustrations, black and white; XVII, 279 p. 47 illus., 10 illus. in color.

Pages

279

Dimensions

155x235x18

ISBN-13

9783540261568

Product ID

5807072

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