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Deterministic Versus Stochastic Modelling in Biochemistry and Systems Biology

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Deterministic Versus Stochastic Modelling in Biochemistry and Systems Biology by Ferenc Jordan

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Stochastic kinetic methods are currently considered to be the most realistic and elegant means of representing and simulating the dynamics of biochemical and biological networks. Deterministic versus stochastic modelling in biochemistry and systems biology introduces and critically reviews the deterministic and stochastic foundations of biochemical kinetics, covering applied stochastic process theory for application in the field of modelling and simulation of biological processes at the molecular scale. Following an overview of deterministic chemical kinetics and the stochastic approach to biochemical kinetics, the book goes onto discuss the specifics of stochastic simulation algorithms, modelling in systems biology and the structure of biochemical models. Later chapters cover reaction-diffusion systems, and provide an analysis of the Kinfer and BlenX software systems. The final chapter looks at simulation of ecodynamics and food web dynamics.

Author Biography

Paola Lecca is a researcher at The Microsoft Research, University of Trento, Centre for Computational and Systems Biology, Italy. Her principal research interests include biochemical system identification and model calibration, stochastic chemical kinetics and reaction-diffusion system. Ian J. Laurenzi is a Senior Researcher at ExxonMobil. He is an expert in the areas of stochastic processes, statistics, computational biology and receptor-mediated adhesion of human blood platelets, and has investigated the genome-level dynamics of gene networks and the effect of sex upon mammalian gene expression. Ferenc Jordan is a biologist whose background is in genetics, theoretical biology and evolutionary biology, and his principal recent interests are systems ecology and biological networks.
Release date NZ
April 9th, 2013
  • Postgraduate, Research & Scholarly
  • Professional & Vocational
  • Undergraduate
Country of Publication
United Kingdom
Woodhead Publishing Ltd
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