Death Receptors and Cognate Ligands in Cancer

Name: Death Receptors and Cognate Ligands in Cancer
SKU: 20835383
Price: 566.00 NZD
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Paperback / softback

Series:

Results and Problems in Cell Differentiation,

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Description

Death receptors play a central role in directing apoptosis in mammalian cells. This process of active cell death is important for a number of biological processes, e.g. for the regulation of the immune system. Death receptors are cell surface receptors that transmit apoptotic signals initiated by corresponding death ligands. Many complex signaling pathways are activated and apoptosis is the final result of a complex biochemical cascade of events. Besides their role in the induction of cell death, evidence now exists that death receptors are able to activate several non-apoptotic signaling pathways which, depending on cellular context, may lead to apoptosis resistance, secretion of pro-inflammatory proteins, proliferation and invasive growth of cancer cells. This book looks at the molecular basis of death receptor signaling and the role of death receptors in cancer development.

Release date NZ

March 14th, 2012

Audience

Professional & Vocational

Contributor

Edited by Holger Kalthoff

Illustrations

9 Illustrations, color; 11 Illustrations, black and white; XIV, 280 p. 20 illus., 9 illus. in color.

Pages

280

Series

Results and Problems in Cell Differentiation,

Dimensions

155x235x16

ISBN-13

9783642260766

Product ID

20835383

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Death Receptors and Cognate Ligands in Cancer

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