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Complement Activation in Malaria Immunity and Pathogenesis on Hardback
Complement Activation in Malaria Immunity and Pathogenesis on Hardback
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Complement Activation in Malaria Immunity and Pathogenesis

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Hardback
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Description

Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes. In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies of P. falciparum merozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite. 

Author Biography:

José A. Stoute, M.D. Professor of Medicine, and Microbiology & Immunology The Pennsylvania State University Hershey Medical Center and College of Medicine
Release date NZ
July 12th, 2018
Audiences
  • Postgraduate, Research & Scholarly
  • Professional & Vocational
Contributor
  • Edited by Jose A. Stoute
Edition
1st ed. 2018
Illustrations
17 Illustrations, color; 5 Illustrations, black and white; XII, 149 p. 22 illus., 17 illus. in color.
Pages
149
ISBN-13
9783319772578
Product ID
27601189

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