Non-Fiction Books:

Chromosomal Translocations and Oncogenic Transcription Factors

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Paperback / softback
$287.00
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Description

Regulation of gene expression at the level of transcription is one of the major determinants of proper cellular proliferation and differentiation. The key players in these processes are sequence-specific DNA binding transcription factor proteins which coordinate programs of gene expression in the nucleus. The articles in this volume document the myriad of genetic and biochemical alterations sustained by human proto-oncogenic transcription factors which result in diverse neoplastic processes. This volume gives insights into how normal programs of gene expression can be subverted by the action of single transcription factors resulting in a specific tumor type. The book provides inspiration for exploiting these tumor-specific alterations as diagnostic, prognostic tools, or as selective therapeutic targets.
Release date NZ
October 2nd, 2011
Audience
  • Professional & Vocational
Contributors
  • Edited by Frank J. III Rauscher
  • Edited by Peter K. Vogt
Edition
Softcover reprint of the original 1st ed. 1997
Illustrations
XI, 166 p.
Pages
166
Dimensions
156x234x9
ISBN-13
9783642644245
Product ID
20761400

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