A firsthand account of the courageous and determined effort, helmed by the author, to combat the devastation caused by the AIDS epidemic in India and later in Asia Pacific region. Fighting immeasurable odds at a time when India carried the second largest disease burden in the world, the author steered the ship of the Indian Government's response through its most critical stage. The story continues as the author takes the reins of UNAIDS, the Joint UN programme on AIDS in the Asia Pacific region, and aligns the organisation to the needs of those countries. The author then presents an unbiased and critical assessment as the Special Envoy to the UN Secretary General on the current faltering of AIDS response in Asia Pacific. This book is a summary of the roles essayed by the author as policy maker, programmer, advocate and activist for HIV/AIDS in a career spanning over two decades.