The book is concerned of the different biomaterials prepared by different methods. The biomaterials were characterized and assessed by in-vitro study in a simulated body fluids (SBF) similar to blood plasma to confirm the formation of a bone-like apatite layer on the material surface via microstructure and elemental analysis pre-and post-immersion in SBF. Also, the formation of a bone-like apatite layer was confirmed by the reduction of calcium and phosphate ions in post-immersion in the SBF. Eventually, all these promising biomaterials can be used as bone substitutes in medical application after in-vivo study. The book is composed of collective research papers of highly applicable biomaterials and benefits scientists in materials science and medical field.