Lactobacillus antibacterial peptides are natural food preservatives. The biological experiment of separating lactic acid bacteria antibacterial peptides is time-consuming and labor-intensive. Computer artificial intelligence technology can quickly identify them in batches. Graph neural network is a popular new technology in recent years, which has been successfully applied in the field of natural language and text processing. Look at the sequence information of antibacterial peptide protein of lactic acid bacteria in the text, and use the information transmission between nodes on the graph to transfer label information and feature information well. At the same time, we also include some cases of intelligent algorithms to solve classical combinatorial optimization problems, hoping to bring scientific inspiration and inspiration to readers.