Asphyxia and Fetal Brain Damage provides an overview of the combined advances in maternal-fetal medicine, neonatology, pediatric neurology, diagnostic imaging, and molecular biology that have altered the way clinicians and researchers understand and manage asphyxial injury to the fetal central nervous system. Featuring contributions from internationally renowned specialists, Asphyxia and Fetal Brain Damage addresses the etiology and mechanism of fetal asphyxia, presents the latest information on possible therapeutic interventions, and explains the scientific basis of a range of fetal surveillance techniques. The book also discusses clinical management protocols for high-risk pregnancies and addresses risk and liability management strategies. Individual chapters address topics such as: Fetal asphyxia and outcome The molecular mechanisms of fetal brain injury Perinatal asphyxia and placental pathology Management strategies for perinatal hypoxic-ischemic encephalopathy Fetal neurosonography Computerized approaches to fetal surveillance Monitoring the growth-retarded fetus Emerging technologies such as fetal optical monitoring Supplemented with over 200 illustrations, Asphyxia and Fetal Brain Damage is an invaluable reference for obstetricians, neonatologists, maternal-fetal specialists, pediatric neurologists, basic scientists, and legal professionals.

Table of Contents

Antecedents of Long--Term Handicap (T. Farrell, et al.).; Fetal Asphyxia and Outcome (J. Low).; Fetal Adaptive Responses to Hypoxia: Physiological Basis for Fetal Monitoring (B. Richardson).; The Molecular Mechanisms of Fetal Brain Injury: The Role of Oxygen Free Radicals (D. Maulik).; Perinatal Asphyxia and Placental Pathology (C. Salafia).; Excitotoxicity and Patterns of Brain Injury From Fetal or Perinatal Asphyxia (M. Johnston & A. Hoon).Management Strategies for Perinatal Hypoxic--Ischemic Encephalopathy (R. Vannucci).; Postnatal Neuroimaging to Time Hypoxic--Ischemic Cerebral Injury (J. Perlman).; How to Time When Hypoxic--Ischemic Fetal Brain Damage Took Place (R. Naeye).; Hematologic Markers to Date Fetal Neurologic Injury (L. Korst & J. Phelan).; Intraventricular Hemorrhage in the Premature Infant (J. Perlman).; Computerized Analysis of Fetal Heart Rate for Recognizing Antepartum Fetal Compromise (D. Arduini, et al.).; Fetal Neurosonography (I. Timor--Tritsch & A. Monteagudo).; The Brain--Damaged Baby: Fetal Heart Rate Lessons from the Data Bank (J. Phelan & M. Ahn).; Computerized Approaches to Fetal Surveillance (L. Devoe).; Fetal Biophysical Variables and Fetal Status (C. Harman, et al.).; Comparative Evaluation of Doppler Waveform in Arteries and Veins Evaluated with Nonstress Test, Contraction Stress Test, and Cord Blood Sampling in Growth--Retarded or Hydropic Fetuses (Y. Chiba).; Monitoring the Growth--Retarded Fetus (G. Visser & R. Stigter).; Emerging Technologies: Fetal Optical Monitoring (M. Stankovic, et al.).; Index.