Non-Fiction Books:

Aging of the Genome

The dual role of DNA in life and death
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Paperback / softback
$262.00
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Description

Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recent advances in functional genomics and systems biology. It provides an up-to-date synthesis of current research, as well as a look ahead to the design of strategies to retard or reverse the deleterious effects of aging. This is particularly important in a time when we are urgently trying to unravel the genetic component of aging-related diseases. Moreover, there is a growing public recognition of the imperative of understanding more about the underlying biology of aging, driven by continuing demographic change.

Author Biography:

Jan Vijg is Professor at the Buck Institute for Age Research in Novato, California, USA
Release date NZ
January 25th, 2007
Author
Audiences
  • Further/Higher Education
  • Professional & Vocational
Illustrations
numerous line drawings, halftones and 4 tables
Pages
386
Dimensions
190x240x20
ISBN-13
9780198569237
Product ID
2124565

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