Non-Fiction Books:

Total Synthesis of Callipeltin E and Towards Papuamide B

Format

Paperback

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Total Synthesis of Callipeltin E and Towards Papuamide B by SELCUK CALIMSIZ
$146.99
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Description

Callipeltins and Papuamides -novel families of cyclic depsipeptides- were shown to possess potent anti-HIV activity as well as cytotoxicity against several multidrug resistant cancer cell lines. The novel structural features and diverse biological effects of these peptides metabolites have generated considerable interest among synthetic chemistry groups. In this book, discovery of the lanthanide catalyzed transamidation of Fmoc protected lactams, solid-phase synthesis and configurational reassignment of Callipeltin E, synthesis of N-Fmoc- (2S,3S,4R)-3,4-dimethylglutamine and an efficient method for the on-resin synthesis and macrocylization of a simplified Papuamide B model system are summarized.
Release date NZ
November 6th, 2008
Country of Publication
Germany
Illustrations
black & white illustrations
Imprint
VDM Verlag
Pages
128
Dimensions
152x229x7
ISBN-13
9783639103298
Product ID
2963943

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