There have been numerous major advances in clinical trial methodology and this superb book will cover all developments in this important field. Written as a successor to the outstandingly successful book by Pocock 'Clinical Trials', it will provide up to date coverage of the topics covered in the original text whilst retaining the same authoritative and didactic approach. It will appeal to a wide readership including clinicians and data managers as well as medics and health care professionals who need to know the simple statistical issues in trials and statisticians who need to know about the medical and other non-statistical aspects of trials.

Author Biography

David Machin, Medical Statistics Group, School of Health and Related Sciences, University of Sheffield, UK and Children's Cancer and Leukaemia Group, University of Leicester, UK. Peter M Fayers, Department of Public Health, University of Aberdeen, UK and Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.