Pain Control

Name: Pain Control
SKU: 23448607
Price: 560.00 NZD
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Format:

Hardback

Series:

Handbook of Experimental Pharmacology

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Description

This volume addresses neuronal pain mechanisms at the peripheral, spinal and supraspinal level which are thought to significantly contribute to pain and which may be the basis for the development of new treatment principles. Chapters on nociceptive mechanisms in the peripheral nociceptive system address the concept of hyperalgesic priming, the role of voltage-gated sodium channels in different inflammatory and neuropathic pain states, the hyperalgesic effects of NGF in different tissues and in inflammatory and neuropathic pain states, and the contribution of proteinase activated receptors (PAR) to the development of pain in several chronic pain conditions. Chapters on nociceptive mechanisms in the spinal cord address the particular role of NO and of glial cell activation in the generation and maintenance of inflammatory and neuropathic pain and it discusses the potential role of local inhibitory interneurons, of the endogenous endocannabinoid system and the importance of non-neuronal immune mechanisms in opioid signaling in the control of pain. Furthermore, it is presented how spinal mechanisms contribute to the expression of peripheral inflammation.

Release date NZ

April 14th, 2015

Audience

Professional & Vocational

Contributor

Edited by Hans-Georg Schaible

Illustrations

22 Illustrations, color; 9 Illustrations, black and white; VIII, 309 p. 31 illus., 22 illus. in color.

Pages

309

Series

Handbook of Experimental Pharmacology

Dimensions

155x235x19

ISBN-13

9783662464496

Product ID

23448607

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