Dr. Carmine Zoccali is an Orthopaedic surgeon who works at the Department of Orthopaedic and Traumatology of Policlinico Umberto I of Rome; moreover, he is a researcher of Sapienza University of Rome. His field of expertise is spine, pelvic and paediatric bone and soft tissues tumor surgery and his research activity is in reconstruction techniques and computer-assisted surgery. He has performed more than 800 operations in muscular skeletal oncology and he is the author of more than 90 papers in international scientific journals.  Prof. Pietro Ruggieri is a Full-professor at the University of Padova; he is one of the most expert surgeons worldwide in muscular-skeletal oncology and he is in the board of the most important world societies of orthopaedics and international journals. He is the author of more than 800 papers in internationals journals.  Prof. Francesco Benazzo is a Full-professor at the University of Pavia; heis one of the most expert surgeons in orthopaedics and traumatology and sports medicine. He is in the board of important scientific societies . He is the author of more than 200  papers in peer reviewed journals.