Framed for the murder of his brother, Geoffrey Radcliffe is scheduled to hang. After a visit from his friend Dr. Frank Griffin, he vanishes mysteriously from prison. Police inspector Sampson realizes that Griffin is the brother of the original Invisible Man and has given Geoffrey the formula to aid his escape. Can Geoffrey elude the police dragnet and track down the real murderer? More importantly, can Griffin discover an antidote before the invisibility formula drives Geoffrey insane?
- " The Invisible Man Returns is at its best when it is not occupying itself with something it would like you to take seriously. " – Harry MacArthur (Washington Star)
- " Stripped of the horror angles of its forerunner, The Invisible Man Returns is a fantastic tale of the impossible – but unfolded in such a manner that it maintains interest throughout despite its basic incredibility. " – Variety Staff
- " The first sequel to the Claude Rains classic, while more modestly scaled than its predecessor, still receives a first-class treatment from director Joe May and, in many instances, surpasses the visual magic of the original. " – Alan Jones (Radio Times)