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The Genetics of African Populations in Health and Disease

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The Genetics of African Populations in Health and Disease

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Description

The birthplace of modern humans, Africa, has the highest genetic diversity in the world, yet it remains vastly understudied. With biomedical research increasingly focused on human variation, studying the large population size and number of mutations in African genomes could unravel the complexity of phenotypic traits underlying the biology of our species and hold huge potential for scientific and medical advances. An initial chapter 'conceptualizes Africa', providing relevant terminology. The first section covers genetic history and population structure. The next section looks at the genetic basis of common infectious diseases, such as leishmaniasis, malaria and tuberculosis, with a final part considering common non-communicable diseases, such as diabetes, hypertension, obesity, heart disease and cancer. Gene environment interaction under globalization and the burden of diseases of lifestyle are included. For researchers and graduate students in biological anthropology, genetic anthropology, human and population genetics, and public health.

Author Biography:

Muntaser E. Ibrahim is a Professor at the Department of Molecular Biology, Institute of Endemic Diseases at the University of Khartoum, Sudan. He established the Unit of Diseases and Diversity at the University in 1998. He is a founding member of the African Society of Human Genetics and, in 2014, won the CNR Rao Prize for Scientific Research. Charles Rotimi is the Chief of the Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch and the Director of the Center for Research on Genomics and Global Health at the National Human Genome Research Institute (NIH), Maryland. He was founding president of the African Society of Human Genetics and spearheaded formation of the H3Africa Initiative.
Release date NZ
December 19th, 2019
Audience
  • Professional & Vocational
Contributors
  • Edited by Charles N. Rotimi
  • Edited by Muntaser E. Ibrahim
Illustrations
10 Tables, black and white; 15 Halftones, black and white; 4 Line drawings, black and white
Pages
348
Dimensions
178x253x20
ISBN-13
9781107072022
Product ID
28474147

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