Nearly 30 years after the first edition was published, The Fifteen Minute Hour: Therapeutic Talk in Primary Care continues to support practitioners in solving and often preventing many psychological and behavioural problems, while enhancing the therapeutic relationship with their patients. The simple and effective techniques are easily learned and designed to increase patient satisfaction without adding significantly to the length of a visit. The Fifth edition is completely updated with new references substantiating the efficacy of the methods employed. New material focuses on findings regarding brain plasticity, gene expression and the epigenetic effects of constructively managing stress while also demonstrating the power of positive affirmation, mindfulness and exercise on enhancing health.