Non-Fiction Books:

The Discovery, Use and Impact of Platinum Salts as Chemotherapy Agents for Cancer

Format

Paperback

Customer rating

Click to share your rating 0 ratings (0.0/5.0 average) Thanks for your vote!

Share this product

The Discovery, Use and Impact of Platinum Salts as Chemotherapy Agents for Cancer
$26.99
In stock with supplier

The item is brand new and in-stock in with one of our preferred suppliers. The item will ship from the Mighty Ape warehouse within the timeframe shown below.

Usually ships within 9-11 days

Availability

Delivering to:

Estimated arrival:

  • Around 12-15 December using standard courier delivery

Description

Serendipity played a large part in the discovery of the biological actions of the simple platinum coordination complexes. In the mid-1960s, Professor Barnett Rosenberg and colleagues found that a simple platinum-based compound prevented bacteria from dividing normally. He tested the compound on cancer cells and showed that it was biologically active. Cisplatin has since emerged as one of the most widely prescribed anticancer agents. Cisplatin has been shown to be effective either alone or in combination for the treatment of a wide variety of solid cancers in man, including testicular and ovarian cancers. It is also palliative in the treatment of cancers of the head and neck, bladder, prostate, lung, cervix, and in some paediatric cancers. Toxic side effects of the drug include damage to the kidney and severe side effects include such nausea and vomiting that patients have been known to refuse treatment. In turn, the cisplatin-induced emesis provided a major stimulus for research into anti-emetics, which has provided several effective drugs for the relief of many kinds of nausea and vomiting, especially that associated with radio- and chemotherapy.The relief of such toxic side effects has been an important factor in encouraging patients to continue successfully otherwise unpleasant forms of cancer therapy. Participants who attended this Witness Seminar include representatives from several areas of work on the platinum compounds: chemists who worked with Rosenberg; oncologists who pioneered their use clinically; and pharmacologists who examined the emetic properties of these compounds, and devised, in particular, the 5HT3 receptor antagonists
Release date NZ
October 1st, 2007
Contributors
Edited by D.A. Christie Edited by E.M. Tansey
Country of Publication
United Kingdom
Illustrations
black & white illustrations
Imprint
Wellcome Trust Centre for the History of Medicine at UCL
Pages
148
Dimensions
235x191x8
ISBN-13
9780854841127
Product ID
1833382

Customer reviews

Nobody has reviewed this product yet. You could be the first!

Write a Review

Marketplace listings

There are no Marketplace listings available for this product currently.
Already own it? Create a free listing and pay just 9% commission when it sells!

Sell Yours Here

Help & options

  • If you think we've made a mistake or omitted details, please send us your feedback. Send Feedback
  • If you have a question or problem with this product, visit our Help section. Get Help
  • Seen a lower price for this product elsewhere? We'll do our best to beat it. Request a better price
Filed under...

Buy this and earn 121 Banana Points