Non-Fiction Books:

Sequence-specific DNA Binding Agents

Format

Hardback

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Sequence-specific DNA Binding Agents
$415.00

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Description

The binding of antibiotics and drugs to DNA is a fast developing area of research with important applications in medicine, particularly the treatment of cancer. Sequence-specific DNA Binding Agents uniquely discusses key aspects of this topic, providing a novel perspective on the subject. Written by experts in the field, this book discusses diverse modes of binding of antibiotics and drugs to DNA, emphasising matters that are important or promising for cancer treatment. Chapters discuss established agents like actinomycin D but also look at novel drugs with strong potential in chemotherapy such as new topoisomerase inhibitors, telomerase inhibitors, peptide nucleic acids and triple helix-forming oligonucleotides. There are also sections discussing methodological advances including computational methods, slow kinetics, melting curve analysis and approaches to medicinal chemistry. Finally there is a section on RNA structure and its potential as a drug target. The book is ideal for researchers in industry and academia who require a comprehensive source of reference to this rapidly expanding subject.
Release date NZ
September 1st, 2006
Contributors
Contributions by Bengt Norden Contributions by Christian Bailly Contributions by Christophe Marchand Contributions by David Rusling Contributions by Dinshaw Patel Contributions by K. R. Fox Contributions by Tom Brown Contributions by Yves Pommier Edited by Michael J Waring Editor-in-chief Stephen Neidle
Country of Publication
United Kingdom
Illustrations
No
Imprint
Royal Society of Chemistry
Pages
270
Dimensions
156x234x21
ISBN-13
9780854043705
Product ID
3865616

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