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Protein oxidation by free radicals is thought to play a major role in many oxidative processes within cells, and is implicated in human disease, carcinogenesis, and ageing. This unique and comprehensive volume brings together up-to-date information on the oxidation of amino acids, peptides, and proteins by free radicals and discusses the roles of such processes in biological systems. Topics include: the chemistry of amino acid and protein oxidation; the biochemical consequences of these reactions; the role of protein oxidation in normal physiology; the potential importance of protein oxidation in human health - including ageing, heart disease, cancer, inflammation and neurodegenerative diseases - and the possible prevention of such processes by antioxidants and other protective strategies.
Professor Roger T. Dean, Director, The Heart Research Institute Ltd, 145-147 Missenden Road, Camperdown, Sydney, New South Wales 2050, Australia. Tel: 0061 2 550 3560. Fax: 0061 2 550 3302. Email: firstname.lastname@example.org
Dr Michael Davies at the same address