Quasispecies: From Theory to Experimental Systems

Name: Quasispecies: From Theory to Experimental Systems
SKU: 27868526
Price: 445.00 NZD
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Paperback / softback

Series:

Current Topics in Microbiology and Immunology

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Description

This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating viral dynamics and treatment designs. In particular, the existence of an error threshold in rugged fitness landscapes has opened the way to a new antiviral strategy termed lethal mutagenesis, which is now under intensive theoretical, experimental and clinical investigation. As such the book explains how an understanding of quasispecies dynamics within infected organisms has increased our knowledge of viral disease events. From a clinical perspective, population dynamics highlights important problems for viral disease control, such as the selection of drug-resistant mutants that often accompanies treatment failures, and suggests means of increasing the effectiveness of antiviral treatments. The book is intended for students and scientists interested in basic and applied aspects of biophysics, chemistry, biology, evolution and medical virology.

Author Biography:

Esteban Domingo is a professor at the Spanish Research Council at Centro de Biología Molecular Severo Ochoa (Madrid) and President of the Spanish Society of Virology. He is a member of EMBO and Real Academía de Ciencias Exactas, Físicas y Naturales. Peter Schuster, em. professor of University of Vienna is a member of Leopoldina, Nationale Akademie der Wissenschaften, National Academy of Sciences USA, European Academy of Sciences and Arts and several other institutions. He worked together with Manfred Eigen and developed together with him the concepts of "quasispecies" and "hypercycles".

Release date NZ

April 19th, 2018

Audience

Professional & Vocational

Contributors

Edited by Esteban Domingo
Edited by Peter Schuster

Edition

Softcover reprint of the original 1st ed. 2016

Illustrations

53 Illustrations, color; 14 Illustrations, black and white; XIV, 357 p. 67 illus., 53 illus. in color.

Pages

357

Series

Current Topics in Microbiology and Immunology

Dimensions

156x234x20

ISBN-13

9783319795485

Product ID

27868526

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