Written by an international group of renowned experts, the Fifth Edition of this premier reference provides comprehensive, current information on the genetics, pathophysiology, diagnosis, medical and surgical treatment, and behavioral and psychologic concomitants of all common and uncommon movement disorders. Coverage includes Parkinson's disease, other neurodegenerative diseases, tremors, dystonia, Tourette's syndrome, Huntington's disease, and ataxias. This edition features extensive updates on genetics, imaging, and therapeutics of Parkinson's disease, other parkinsonian disorders, and all hyperkinetic movement disorders. A bound-in CD-ROM, Video Atlas of Movement Disorders, demonstrates the movement and posture abnormalities and other disturbances associated with Parkinson's disease and other neurologic disorders.

Table of Contents

Functional Organization of the Basal Ganglia Neurophysiology of Motor Control and Movement Disorders Neurobehavioral Disorders Associated with Basal Ganglia Lesions Protein Mishandling: Role of the Ubiquitin Proteasome System in the Pathogenesis of Parkinson's Disease Epidemiology of Movement Disorders Non-Motor Symptoms in Parkinson's Disease Etiology and Pathogenesis of Parkinson's Disease Genetics of Parkinson's Disease Disease-Modifying Strategies in Parkinson's Disease Pharmacological Management of Parkinson's Disease Experimental Therapeutics of Parkinson's Disease Dementia Associated with Parkinson's Disease: Features and Management Progressive Supranuclear Palsy Multiple System Atrophy Corticobasal Degeneration Inherited and Sporadic Tauopathies Secondary Parkinsonism Huntington's Disease Choreas, Athetosis, and Ballism Neurodegeneration with Brain Iron Accumulation Wilson's Disease Neuropathology of Parkinsonian Disorders Mitochondrial Movement Disorders Tremors: Differential Diagnosis, Pathophysiology, and Therapy Dystonic Disorders Treatment of Dystonia Tics and Tourette's Syndrome Myoclonus and Startle Syndrome Treatment of Myoclonus Drug Induced Movement Disorders Restless Leg Syndrome Hereditary Ataxias Gait Disorders Paroxysmal Dyskinesias: An Overview Stereotopy and Catatonia Childhood Movement Disorders Rigidity and Spasticity Muscle Cramps, Stiffness, and Myalgia Assessment of Behavior in Parkinsonian Disorders Psychogenic Movement Disorders Neuroacanthocytosis Prion Diseases Functional Neuroimaging in Movement Disorders Botulinum Toxin in Movement Disorders Surgery for Hyperkinetic Movement Disorders Human Embryonic Stem Cell-Based Therapy for Parkinson's Disease Deep Brain Stimulation Clinical Rating Scales in Movement Disorders