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Medical Genetics for the Modern Clinician



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Medical Genetics for the Modern Clinician by Judith A. Westman
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"Medical Genetics for the Modern Clinician" is a concise, clinically oriented introductory genetics text for medical and allied health students, residents, and clinicians. The book focuses sharply on concepts that are most applicable to clinical practice. Ethics sections in each chapter discuss ethical issues facing today's practitioner, such as counseling, risk assessment, and testing. More than 120 illustrations help students visualize concepts. Each chapter ends with USMLE-style review questions. Appendices include a glossary and a Table of Genes that lists all genes covered in the text by chapter.

Table of Contents

CHAPTER 1: GENETICS IN THE PRACTICE OF MEDICINE From Genetics to Genomics Genetics and Preventive Medicine Ethical Issues in Medical Genetics USMLE-Style Questions CHAPTER 2: DNA STRUCTURE, FUNCTION, AND REPLICATION: A REVIEW Basic Structure of DNA Tertiary Structure of DNA Mitochondrial DNA Cell Cycle Meiosis USMLE-Style Questions CHAPTER 3: CYTOGENETICS: MICROSCOPIC GENETICS Chromosome Morphology, Nomenclature, and Karyotyping Techniques in Molecular Cytogenetics Numerical Chromosomal Abnormalities Structural Abnormalities Mosaicism Prenatal Clinical Techniques in Cytogenetics USMLE-Style Questions CHAPTER 4: MOLECULAR GENETICS: GENE STRUCTURE, ORGANIZATION, AND CONTROL Gene Structure From Gene to Product Genome Organization Epigenetics Clinically Relevant Laboratory Techniques USMLE-Style Questions CHAPTER 5: Changes and Repair at the Molecular DNA Level Mutations DNA Repair Mechanisms SMLE-Style Questions CHAPTER 6: MENDELIAN INHERITANCE: OBSERVATION OF PHENOTYPES Pedigree Construction Inheritance Patterns Genetic Counseling Risk Assessment Based on Pedigree Analysis Hardy-Weinberg Equilibrium Prenatal Diagnosis of Mendelian Disorders USMLE-Style Questions CHAPTER 7: UNEXPECTED PHENOTYPES IN MENDELIAN DISORDERS: MOLECULAR EXPLANATIONS Variations in Dominant Phenotypes Variations in Recessive Phenotypes Variations in X-linked Phenotypes Mitochondrial Inheritance False Paternity USMLE-Style Questions CHAPTER 8: CANCER GENETICS Genes and Cancer Multistep Evolution in Cancer Cancer Risk Assessment Counseling Oncogenes Tumor Suppressor Genes USMLE-Style Questions CHAPTER 9: COMPLEX DISEASES Threshold Model Modifier Genes Tools for Study of Complex Diseases Congenital Complex Diseases Adult-Onset Complex Diseases USMLE-Style Questions CHAPTER 10: DEVELOPMENTAL GENETICS Dysmorphology Embryologic Development and Control Mechanisms USMLE-Style Questions CHAPTER 11: INDIVIDUALIZED MEDICINE Pharmacogenomics Individualized Drug Therapies Disease Susceptibility USMLE-Style Questions CHAPTER 12: GENE THERAPY Viral Vectors Nonviral Vectors USMLE-Style Questions Appendix: Answers to USMLE-Style Questions Appendix: Glossary Appendix: Table of Genes Referenced
Release date NZ
April 1st, 2005
Country of Publication
United States
100 illustrations
Lippincott Williams and Wilkins
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