In the liver, nutrients taken up from food are utilized for the synthesis of different components of the body, and the waste matter and harmful substances produced are disposed or detoxicated. These functions of the liver must be regulated in accordance with the state of the body. The nervous system plays this regulatory role, one which is reminiscent of the production management system in a factory. This work reviews all aspects of neuro-hepatology, especially in relation to the neural control of liver function. It covers the following topics: anatomy and organizational structure of extrinsic and intrinsic nerves of the liver; intercellular communication of liver cells and nerves; metabolic effects of liver nerves, including hepatic gene expression; haemodynamic effects of liver nerves; physiological roles for hepatic afferents; neuropharmacology, including co-transmitters and receptors; clinical implications of liver innervation, such as in liver transplantation, liver regeneration and liver diseases; and new aspects of neural regulation. The book should be of interest to physiologists, biochemists, neuro-scientists and clinical investigators.