"Janeway's Immunobiology, Seventh Edition" is an introductory text for use in immunology courses for undergraduates, graduate students and medical students. It guides the reader through the immune system in all its aspects - from the first engagement of innate immunity to the generation of the adaptive immune response and its clinical consequences. The Seventh Edition has been comprehensively updated throughout, and includes new information on topics such as NK cells, Toll-like receptors, AID, viral evasins, mucosal immunity, and celiac disease, to name a few.Each copy of the book includes a revised CD-ROM, Immunobiology Interactive, which contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes. "Janeway's Immunobiology" continues to set the standard for currency and authority with its clear writing style and organization, full-color art program, scientific accuracy and consistent viewpoint - that of the host's interaction with an environment containing many species of potentially harmful microorganisms.
Table of Contents
Part I An Introduction to Immunobiology and Innate Immunity 1. Basic Concepts in Immunology 2. Innate Immunity Part II The Recognition of Antigen 3. Antigen Recognition by B-cell and T-cell Receptors 4. The Generation of Lymphocyte Antigen Receptors 5. Antigen Presentation to T Lymphocytes Part III The Development of Mature Lymphocyte Receptor Repertoires 6. Signaling Through Immune System Receptors 7. The Development and Survival of Lymphocytes Part IV The Adaptive Immune Response 8. T Cell-Mediated Immunity 9. The Humoral Immune Response 10. Dynamics of Adaptive Immunity 11. The Mucosal Immune System Part V The Immune System in Health and Disease 12. Failures of Host Defense Mechanism 13. Allergy and Hypersensitivity 14. Autoimmunity and Transplantation 15. Manipulation of the Immune Response Part VI The Origins of Immune Responses 16. Evolution of the Immune System Appendix I Immunologists' Toolbox Appendix II CD Antigens Appendix III Cytokines and their Receptors Appendix IV Chemokines and their Receptors Appendix V Immunological Constants
Kenneth M. Murphy, Washington University School of Medicine, St. Louis, USA. Paul Travers, Scottish Centre for Regenerative Medicine, UK. Mark Walport, The Wellcome Trust, UK.