Iron Acquisition by the Genus Mycobacterium

Name: Iron Acquisition by the Genus Mycobacterium
SKU: 21250037
Price: 148.00 NZD
Availability: InStock

History, Mechanisms, Role of Siderocalin, Anti-Tuberculosis Drug Development

Format:

Paperback / softback

Series:

Springerbriefs in Molecular Science

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Description

Iron Acquisition by the Genus Mycobacterium summarizes the early evidence for the necessity of iron in mycobacteria and the discovery of the mycobacterial siderophores mycobactin, carboxymycobactin, and exochelin. The structural characterization of the mycobacterial siderophores is described. The genes so far identified as essential for iron acquisition and maintenance of an infection by pathogenic mycobacteria are discussed. The potential role of siderocalin in iron gathering by M. tuberculosis is featured. Because new drugs for M. tuberculosis are needed, this brief also emphasizes the design of antibiotics that interfere with siderophore biosynthesis and the use of siderophore analogs and/or conjugates.

Release date NZ

June 3rd, 2013

Audience

Professional & Vocational

Contributor

Edited by B. Rowe Byers

Illustrations

9 Illustrations, color; 30 Illustrations, black and white; V, 92 p. 39 illus., 9 illus. in color.

Pages

Series

Springerbriefs in Molecular Science

Dimensions

155x235x6

ISBN-13

9783319003023

Product ID

21250037

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