The world chronicle of Jo(h)annes Antiochenus is a decisive source in the development of Christian universal historiography and world chronicles in the Christian Orient. It stretches from Adam to the beginning of the reign of Heraclius (610). The author was an educated official in the imperial administration in Constantinople. The chronicle was written in the context of the cultural and political debate about the renewal of the Emperorship after the deposition of the tyrant Phokas (October 610); the model is provided by the political structure of the Roman republic. This is the first time that the chronicle has been made available in a modern edition (with an Italian translation) and a detailed introduction. The edition of the fragments includes above all new texts on Greek prehistory, Roman history, the chronology of biblical and Greek history, and on the history, topography and archaeology of Constantinople.