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Imaging, Manipulation and Optogenetics in Zebrafish on Hardback by Itia Amandine Favre-Bulle
Imaging, Manipulation and Optogenetics in Zebrafish on Hardback by Itia Amandine Favre-Bulle
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Imaging, Manipulation and Optogenetics in Zebrafish

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Description

The work described here investigates the advantages and limitations of using laser light for the deep in-vivo illumination and micromanipulation of the neuronal system in zebrafish. To do so, it combines and develops novel optical methods such as optogenetics, light sheet microscopy and optical micromanipulation. It also demonstrates, for the first time, that directional and focused laser beams can successfully be used to target large objects at considerable depth in a living organism to exert purely optical force – in this case on otoliths (ear stones) – and create fictive vestibular stimuli in a stationary animal. The behavioural study and simultaneous imaging of the whole brain reveal the location of the brain cells specific to each ear stone. Elucidating these fundamental neural processes holds substantial value for basic neuroscience researchers, who still have only a vague grasp of how brain circuits mediate perception. As such, it represents highly innovative research that has already led to high-impact publications and is now being intensively pursued.
Release date NZ
August 21st, 2018
Audience
  • Professional & Vocational
Edition
1st ed. 2018
Illustrations
23 Illustrations, color; 26 Illustrations, black and white; XVIII, 86 p. 49 illus., 23 illus. in color.
Pages
86
ISBN-13
9783319962498
Product ID
28228029

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Imaging, Manipulation and Optogenetics in Zebrafish by Itia Amandine Favre-Bulle
$295.00
Imaging, Manipulation and Optogenetics in Zebrafish
by Itia Amandine Favre-Bulle ~ Paperback / softback
Available - Usually ships in 3-4 weeks

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