As the legacy of the Creators is uncovered, the assault on Chronos begins at last! Separated from friends and hounded by enemies, Sho and Mizuki seek refuge in a small town to escape their relentless assailants. However, they soon find that the tiny haven is nothing more than a deadly trap after the entire town transforms into a ruthless army of Zoanoids. Aided by Makishima, Sho is reunited with his friends and finds unlikely new allies in a group of renegade Chronos scientists. Stationed at the bottom of Relic's Point, Sho and company construct a plan to launch a counter-attack on Chronos by activating a long-buried Creator spaceship hidden beneath the base. Unfortunately, Guyot has plans of his own, as he uncovers a way to remove the Guyver units from their hosts and equip them to himself. Chaos erupts as Guyvers, Zoalords and the ancient technology of the Creators collide in a desperate struggle for power.